IL-11 Inhibition Extends Mouse Lifespan by 29%: A Breakthrough Rivaling Rapamycin’s Effects
TL;DR: A 2024 Nature study shows that inhibiting interleukin-11 (IL-11) extends median mouse lifespan by 28.7% when administered at an age equivalent to human late-50s, with improved health markers and reduced tumor incidence. This extension rivals that seen with rapamycin, raising questions about whether IL-11 inhibition works through similar or complementary mechanisms. Key Findings Lifespan […]