clinical trials

SGLTi as a Geroprotective Agent: Comprehensive Review of Clinical Benefits and Mechanisms

TL;DR: SGLTi, originally developed for type 2 diabetes, shows promise as a geroprotective agent that may slow aging, prevent age-related diseases, and improve life expectancy. Its mechanisms of action include promoting autophagy, restoring mitochondrial health, reducing oxidative stress, and decreasing inflammation. Large clinical studies demonstrate reduced risks for many common age-related conditions and improved overall […]

aging research, autophagy, cancer prevention, cardiovascular protection, clinical trials, diabetes treatment, drug repurposing, healthspan, inflammation, lifespan extension, longevity medicine, mitochondrial health, neuroprotection, oxidative stress, renal protection, SGLTi

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Research

The 2024 Longevity Breakthrough: From Mouse Models to Human Potential – A Comprehensive Review of Bill Falloon’s RAADfest Presentation

TL;DR Bill Falloon presents compelling recent advances in age reversal research, particularly focusing on young plasma therapies and OS (Yamanaka) transcription factors. Key 2024 breakthroughs include exosome-rich young plasma cutting epigenetic age in half in rats and OS factors doubling remaining lifespan in aged mice. These interventions are now moving to primate studies, with potential

aging biomarkers, anti-aging interventions, clinical trials, DNA methylation, epigenetic aging, exosome therapy, life extension, longevity research, regenerative medicine, research, science, Yamanaka factors, young plasma

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