cardiovascular protection

Nutrition

Long-Term Sardine Consumption and Gender-Equalized Longevity: 10-Year Results from a Portuguese Cohort Study

Summary of Key Findings This paper reports on a 20-year study examining whether regular sardine consumption affects longevity and reduces gender gaps in life expectancy. The study tracked 400 participants (200 Portuguese and 200 Portuguese-Canadians) who consumed sardines every other day for 10 years. Study Design and Participants Key Results After 10 Years Theoretical Background […]

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Research

Spermidine Intake Reduces Mortality Risk by 24% in 20-Year Human Study: Dietary Polyamine Shows Anti-Aging Effects Equivalent to Being 5.7 Years Younger

Main Findings This prospective study provides the first evidence that higher dietary spermidine intake significantly reduces all-cause mortality in humans. The research demonstrates a strong dose-response relationship, with participants in the highest tertile of spermidine consumption showing mortality risks equivalent to being 5.7 years younger. Study Design and Population Primary Cohort: Bruneck Study Validation Cohort:

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Spermidine Intake Reduces Mortality Risk by 24% in 20-Year Human Study: Dietary Polyamine Shows Anti-Aging Effects Equivalent to Being 5.7 Years Younger Read Post »

Nutrition

Maximizing Coffee’s Health Benefits for Longevity

This video provides a comprehensive guide on how to maximize the health and longevity benefits of coffee while minimizing potential negative side effects. Key Takeaways 1. Longevity and Cardiovascular Health 2. Optimal Timing for Consumption 3. Metabolic and Cancer Risk Reduction 4. Gut Health Benefits 5. Brewing Method and Bean Selection 6. Caffeine vs. Decaf

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Research

SGLTi as a Geroprotective Agent: Comprehensive Review of Clinical Benefits and Mechanisms

TL;DR: SGLTi, originally developed for type 2 diabetes, shows promise as a geroprotective agent that may slow aging, prevent age-related diseases, and improve life expectancy. Its mechanisms of action include promoting autophagy, restoring mitochondrial health, reducing oxidative stress, and decreasing inflammation. Large clinical studies demonstrate reduced risks for many common age-related conditions and improved overall

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