calorie restriction

Research

Spermidine Intake Reduces Mortality Risk by 24% in 20-Year Human Study: Dietary Polyamine Shows Anti-Aging Effects Equivalent to Being 5.7 Years Younger

Main Findings This prospective study provides the first evidence that higher dietary spermidine intake significantly reduces all-cause mortality in humans. The research demonstrates a strong dose-response relationship, with participants in the highest tertile of spermidine consumption showing mortality risks equivalent to being 5.7 years younger. Study Design and Population Primary Cohort: Bruneck Study Validation Cohort: […]

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Spermidine Intake Reduces Mortality Risk by 24% in 20-Year Human Study: Dietary Polyamine Shows Anti-Aging Effects Equivalent to Being 5.7 Years Younger Read Post »

Research

Fasting and Calorie Restriction Effects on Lifespan: Insights from a 960-Mouse Study with Human Biomarker Validation

TL;DR: A large-scale mouse study (n=960) found that both fasting and calorie restriction (CR) extended lifespan, with 40% CR showing the most dramatic results (36% increase in median lifespan). The 40% CR group also maintained youthful physical activity levels throughout life. Key biomarkers like lymphocyte count and red blood cell distribution width (RDW) strongly predicted

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Fasting and Calorie Restriction Effects on Lifespan: Insights from a 960-Mouse Study with Human Biomarker Validation Read Post »

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